SPIRULINA RESEARCH

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There have been many clinical studies conducted on Spirulina and they are ongoing, click the links below to read more.

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Published Third-Party Scientific Research on Spirulina

Scientific name: Arthrospira Platensis.

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FEB 2014 / NEW Anti-cancer effects of blue-green alga Spirulina platensis, a natural source of bilirubin-like tetrapyrrolic compounds.

Spirulina platensis and its tetrapyrrolic components substantially decreased the proliferation of experimental pancreatic cancer. These data support a chemopreventive role of this edible alga………….

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Antioxidant potential of selected Spirulina platensis preparations.

Recent studies suggest that Spirulina, a unicellular blue-green alga, may have a variety of health benefits and therapeutic properties………….

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The effects of spirulina on allergic rhinitis.

The prevalence of allergic rhinitis is increasing globally due to various causes. It affects the quality life of a large group of people in all around the world.………….

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Studies on evaluation of natural products for antiviral effects and their applications.

In the search for novel antiviral molecules from natural products, we have discovered various antiviral molecules with characteristic mechanisms of action.…………

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C-Phycocyanin inhibits cell proliferation and may induce apoptosis in human HepG2 cells.

C-Phycocyanin (C-Pc) is one of the major biliprotein pigments of unicellular cyanbacterium of Spirulina platenesis, it has nutritional, medicinal, and hepatoprotectant application.…………

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A randomized study to establish the effects of spirulina in type 2 diabetes mellitus patients.

Spirulina is a microscopic and filamentous cyanobacterium that contains essential amino acids, essential fatty acids, vitamins, minerals and anti-oxidative components.………….

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Nutritional and therapeutic potential of Spirulina.

Spirulina, a filamentous cyanobacterium, possesses diverse biological activities and nutritional significance due to high concentration of natural nutrients…………

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Preventive effects of Spirulina platensis on skeletal muscle damage under exercise-induced oxidative stress.

The effects of spirulina supplementation on preventing skeletal muscle damage on untrained human beings were examined.……….

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Role of Spirulina in the Control of Glycemia and Lipidemia in Type 2 Diabetes Mellitus.

Spirulina, with its high concentration of functional nutrients, is emerging as an important therapeutic food.……….

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United States pharmacopeia safety evaluation of spirulina.

The Dietary Supplements Information Expert Committee (DSI-EC) of the United States Pharmacopeial Convention (USP) reviews the safety of dietary supplements………..

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Inhibitory activities of microalgal extracts against Epstein-Barr virus DNA release from lymphoblastoid cells.

This study aimed to assess the inhibitory activities of methanol extracts from the microalgae Ankistrodesmus convolutus, Synechococcus elongatus, and Spirulina platensis against Epstein-Barr virus……….

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The effects of Spirulina on anemia and immune function in senior citizens.

Anemia and immunological dysfunction (i.e. immunosenescence) are commonly found in older subjects and nutritional approaches are sought to counteract these phenomena. Spirulina is………….

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Protective effect of aqueous extract from Spirulina platensis against cell death induced by free radicals.

Spirulina is a commercial alga well known to contain various antioxidants, especially phycocyanin.………….

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Hypolipidemic, antioxidant, and antiinflammatory activities of microalgae Spirulina.

Spirulina is free-floating filamentous microalgae growing in alkaline water bodies. With its high nutritional value, Spirulina has been consumed as food for centuries in Central Africa.…………

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Ergogenic and antioxidant effects of spirulina supplementation in humans.

Spirulina is a popular nutritional supplement that is accompanied by claims for antioxidant and performance-enhancing effects. Therefore,…………

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Induction of G1 cell cycle arrest and mitochondria-mediated apoptosis in MCF-7 human breast carcinoma cells by selenium-enriched Spirulina extract.

Both selenium (Se) and Spirulina have been demonstrated to show anticancer potential. In the present study, we showed that Se-enriched Spirulina platensis extract (Se-SE) inhibited the growth of MCF-7 human breast cancer cells………….

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Potential complementarity of high-flavanol cocoa powder and spirulina for health protection.

Recent studies show that ingestion of flavanol-rich cocoa powder provokes increased endothelial production of nitric oxide – an effect likely mediated by epicatchin – and thus may have considerable potential for promoting vascular health.…………

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Complementary and alternative medicine for allergic rhinitis.

Otolaryngologists and other physicians who diagnose and treat allergic rhinitis encounter patients who use complementary medicine and alternative remedies. This article reviews the recent literature……….

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Spirulina in Clinical Practice: Evidence-Based Human Applications.

Spirulina or Arthrospira is a blue-green alga that became famous after it was successfully used by NASA as a dietary supplement for astronauts on space missions.……….

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Spirulina in health care management.

Spirulina is a photosynthetic, filamentous, spiral-shaped and multicellular edible microbe. It is nature’s richest and most complete source of nutrition. Spirulina has a unique blend of nutrients that no single source can offer.………..

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A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans.

This study was conducted to determine the antioxidant capacity, immunomodulatory and lipid-lowering effects of spirulina in healthy elderly subjects and to document the effectiveness of spirulina as a functional food for the elderly.……….

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Inhibition activity of spirulina platensis proteins photo-immobilization biomaterial on proliferation of cancer cells.

The bioactive protein-phycocyanin and all the proteins of Spirulina Platensis were isolated and purified. Photo-reactive proteins were synthesized ………….

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Inhibition of tumor invasion and metastasis by calcium spirulan (Ca-SP), a novel sulfated polysaccharide derived from a blue-green alga, Spirulina platensis.

We have investigated the effect of calcium spirulan (Ca-SP) isolated from a blue-green alga, Spirulina platensis, which is a sulfated polysaccharide chelating calcium and mainly composed of rhamnose, on invasion of B16-BL6 melanoma…………

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Inhibition of HIV-1 replication by an aqueous extract of Spirulina platensis (Arthrospira platensis).

An aqueous extract of the blue-green filamentous algae Arthrospira platensis (previously called Spirulina platensis) inhibited HIV-1 replication in human T-cell lines…………

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Evaluation of chemoprevention of oral cancer with Spirulina fusiformis.

The blue-green microalgae Spirulina, used in daily diets of natives in Africa and America, have been found to be a rich natural source of proteins, carotenoids, and other micronutrients. Experimental studies in animal models have demonstrated an inhibitory effect of Spirulina algae on oral carcinogenesis.………….

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Microalgae as food and supplement.

The microalgae Chlorella spp., Dunaliella spp., and Scenedesmus spp., and the cyanobacteria Spirulina spp., and Aphanizomenon flos-aquae, are being used as nutrient-dense foods…………

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Alteration of mitochondrial membrane potential by Spirulina platensis C-phycocyanin induces apoptosis in the doxorubicinresistant human hepatocellular-carcinoma cell line HepG2.

C-PC (C-phycocyanin) is a water-soluble biliprotein from the filamentous cyanobacterium Spirulina platensis with potent antioxidant, anti-inflammatory and anticancerous properties.……….

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Antiviral activity of Arthrospira-derived spirulan-like substances.

Natural substances offer interesting pharmacological perspectives for antiviral drug development in regard to broad-spectrum antiviral properties and novel modes of action.……….

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Nutrition rehabilitation of HIV-infected and HIV-negative undernourished children utilizing spirulina.

The objective of this study was to assess the impact of an alimentary integrator composed of spirulina (Spirulina platensis; SP), produced at the Centre Médical St Camille of Ouagadougou, Burkina Faso………..

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Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients.

Spirulina represents a blue-green alga that is widely produced and commercialized as a dietary supplement for modulating immune functions, as well as ameliorating a variety of diseases.……….

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Microalgae Spirulina in human nutrition.

Spirulina microalgae (Spirulina platensis, Spirulina maxima, Spirulina fusiformis) is considered as a valuable additional food source of some macro- and micronutrients including high quality protein, iron, gamma-linolenic fatty acid, carotenoids, vitamins B1………….

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Inhibition of enterovirus 71-induced apoptosis by allophycocyanin isolated from a blue-green alga Spirulina platensis.

Enterovirus 71 infection causes significant morbidity and mortality in children, yet there is no effective treatment. In this study, a protein-bound pigment, allophycocyanin purified from blue-green algae is first reported to exhibit anti-enterovirus 71 activity. ………….

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Antioxidant and antiproliferative activities of Spirulina and Chlorella water extracts.

Liver fibrosis is a chronic liver disease that will further develop to cirrhosis if severe damage continues to form. A potential treatment for liver fibrosis is to inhibit activated hepatic stellate cell (HSC) proliferation and, subsequently, to induce HSC apoptosis.…………

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Isolation of three high molecular weight polysaccharide preparations with potent immunostimulatory activity from Spirulina platensis, aphanizomenon flos-aquae and Chlorella pyrenoidosa.

This research describes the identification of three new high molecular weight polysaccharide preparations isolated from food-grade microalgae that are potent activators of human monocytes/macrophages: “Immulina” from Spirulina platensis,…………

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Algae — a poor man’s HAART?

Drawing inferences from epidemiologic studies of HIV/AIDS and in vivo and in vitro HIV inhibition by algae, we propose algal consumption as one unifying characteristic of countries with anomalously low rates.………….

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The effect of ultrasonificated extracts of Spirulina maxima on the anticancer activity.

The effect of ultrasonic extraction on extraction yields, cytotoxicity, and anticancer activity of Spirulina maxima was investigated in this study.………….

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All available third-party research can be found at www.pubmed.gov